Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751529 | 0.79 | HTR4 (0.51) | FAAHITGB3ITGA2BHTR4LMNA | |
| SCHEMBL10752091 | 0.79 | ALDH1A1 (0.50) | CNR2MAOBKMT2AMAOAITGB3 | |
| SCHEMBL10869872 | 0.78 | FAAH (0.45) | FAAHHTR2CCNR2KMT2AMAOA | |
| SCHEMBL1581866 | 0.75 | ACHE (0.62) | HTR2CHTR4 | |
| SCHEMBL10748667 | 0.74 | ALDH1A1 (0.46) | KMT2AMAOAITGB3ITGA2BHTR4 | |
| SCHEMBL27841342 | 0.74 | RAB9A (0.52) | CNR2RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL456356 | 0.72 | RAB9A (0.43) | CNR2RAB9A | |
| SCHEMBL10750771 | 0.72 | LMNA (0.45) | HTR2CITGB3ITGA2BHTR4LMNA | |
| Acetic Acid SCHEMBL10751879 | 0.72 | ALDH1A1 (0.45) | KMT2AMAOAITGB3ITGA2BHTR4 | |
| SCHEMBL11251566 | 0.72 | KMT2A (0.68) | KMT2AITGB3ITGA2BCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665076-A | ANTIARRHYTHMIA AGENTS | RHONE-POULENC SANTE (FR) | 1987-05-12 | — | — | US | disclosed |