Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949081 | 0.87 | MAOA (0.49) | FAAHCNR1CNR2MAOAADRB2 | |
| SCHEMBL11169781 | 0.86 | KMT2A (0.59) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10868748 | 0.81 | LMNA (0.55) | HTR4NCF1PREP | |
| Cinchotoxin SCHEMBL5677046 | 0.79 | CYP2D6 (0.35) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| Cinchotoxin SCHEMBL11766533 | 0.79 | CYP2D6 (0.35) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| Cinchotoxin SCHEMBL11471478 | 0.79 | CYP2D6 (0.35) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| Cinchotoxin SCHEMBL11471479 | 0.79 | CYP2D6 (0.35) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| Cinchotoxin SCHEMBL5677040 | 0.79 | CYP2D6 (0.35) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10752091 | 0.79 | ALDH1A1 (0.50) | HTR4CNR1CNR2MAOACHRNB2 | |
| SCHEMBL10870850 | 0.79 | KDM4E (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613607-A | ANTIARRYTHMIA AGENTS | PHARMUKA LABORATOIRES (FR) | 1986-09-23 | — | — | US | disclosed |
| US-4299835-A | ANXIOLYTICS | PHARMINDUSTRIE (FR) | 1981-11-10 | — | — | US | disclosed |
| US-4237139-A | TRANQUILIZERS, ANTIDEPRESSANTS | PHARMINDUSTRIE (FR) | 1980-12-02 | — | — | US | disclosed |