SCHEMBL10752158

SCHEMBL10752158

CN(C(=O)CBr)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FSCN1 Q16658 1/20 0.40
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
GAA P10253 2/20 0.38
HPGD P15428 2/20 0.38
GLA P06280 1/20 0.38
LMNA P02545 2/20 0.33
ABCB1 P08183 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GSK3B P49841 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
CYP3A4 P08684 2/20 0.32
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11568609 0.76 FSCN1 (0.44) FSCN1ALDH1A1KDM4EGAAHPGD
SCHEMBL2089846 0.76 FSCN1 (0.44) FSCN1ALDH1A1KDM4EGAAHPGD
SCHEMBL2089844 0.76 FSCN1 (0.44) FSCN1ALDH1A1KDM4EGAAHPGD
SCHEMBL2095068 0.75 ABCB1 (0.44) FSCN1ALDH1A1KDM4EGAAHPGD
SCHEMBL7501648 0.72 GSK3B (0.47) ALDH1A1KDM4EHPGDGSK3BPOLB
SCHEMBL5794841 0.68 ALDH1A1 (0.37) FSCN1ALDH1A1KDM4EGAAHPGD
SCHEMBL2095066 0.68 FSCN1 (0.41) FSCN1ALDH1A1KDM4EGAAHPGD
SCHEMBL21765667 0.67 KMT2A (0.46) ALDH1A1HPGDLMNAPOLBSMN1; SMN2
SCHEMBL19881717 0.66 GPR35 (0.38) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL11320156 0.66 FSCN1 (0.36) FSCN1ALDH1A1KDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4661494-A POWDERY MILDEW CHEVRON RESEARCH COMPANY (US) 1987-04-28 US disclosed
US-4532251-A N-substituted-N',N'-disubstituted glycinamide fungicides CHEVRON RESEARCH COMPANY (US) 1985-07-30 US disclosed