Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756515 | 0.96 | POLB (0.70) | POLBALDH1A1SMN1; SMN2EPHX2EPHX1 | |
| SCHEMBL10853163 | 0.90 | POLB (0.76) | POLBALDH1A1SMN1; SMN2EPHX2EPHX1 | |
| SCHEMBL10854103 | 0.86 | POLB (0.70) | POLBALDH1A1SMN1; SMN2EPHX2EPHX1 | |
| SCHEMBL10756618 | 0.77 | RAB9A (0.54) | ALDH1A1RAB9ANAMPTMEN1KMT2A | |
| SCHEMBL4010312 | 0.75 | EPHX2 (0.77) | POLBALDH1A1EPHX2EPHX1RAB9A | |
| SCHEMBL9903230 | 0.74 | ALDH1A1 (0.54) | POLBALDH1A1EPHX2 | |
| SCHEMBL10758782 | 0.74 | RAB9A (0.50) | ALDH1A1SMN1; SMN2RAB9ANAMPTMEN1 | |
| SCHEMBL10753478 | 0.74 | CDK2 (0.52) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL22659944 | 0.74 | POLB (0.75) | POLBALDH1A1SMN1; SMN2EPHX2EPHX1 | |
| SCHEMBL9902657 | 0.73 | ALDH1A1 (0.52) | POLBALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707478-A | ANTIPROTOZOA AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |