Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903230 | 0.95 | ALDH1A1 (0.54) | ALDH1A1POLBEPHX2 | |
| SCHEMBL9902487 | 0.92 | ALDH1A1 (0.47) | ALDH1A1POLBEPHX2 | |
| SCHEMBL14045968 | 0.83 | EPHX2 (0.48) | ALDH1A1POLBEPHX2 | |
| SCHEMBL9903173 | 0.83 | EPHX1 (0.47) | ALDH1A1EPHX2 | |
| SCHEMBL9901315 | 0.83 | ALDH1A1 (0.50) | ALDH1A1POLBEPHX2 | |
| SCHEMBL9902315 | 0.78 | EPHX1 (0.49) | ALDH1A1POLBEPHX2 | |
| SCHEMBL9902595 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1EPHX2 | |
| SCHEMBL9902968 | 0.75 | EPHX1 (0.41) | EPHX2 | |
| SCHEMBL9901557 | 0.74 | CTSL (0.46) | ALDH1A1EPHX2 | |
| SCHEMBL9902992 | 0.74 | ALDH1A1 (0.51) | ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |