Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979785 | 0.80 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1POLBALOX15 | |
| SCHEMBL29464867 | 0.80 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1POLBALOX15 | |
| Hydrochloric Acid SCHEMBL10563346 | 0.78 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1POLBALOX15 | |
| SCHEMBL3499813 | 0.76 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1POLBALOX15 | |
| SCHEMBL29177611 | 0.73 | RXFP1 (0.60) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL28220202 | 0.70 | RXFP1 (0.57) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL10665791 | 0.70 | HTR7 (0.49) | — | |
| SCHEMBL10474332 | 0.70 | IDO1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL1765925 | 0.70 | BACE1 (0.48) | KMT2AALDH1A1 | |
| SCHEMBL5648662 | 0.68 | L3MBTL1 (0.48) | RAB9ASMN1; SMN2NPC1POLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642308-A | ANTICONVULSANTS, ANXIOLYTIC AGENTS, ANTIEPILEPTIC AGENTS, HYPNOTICS, MUSCLE RELAXANTS | RHONE-POULENC SANTE (FR) | 1987-02-10 | — | — | US | disclosed |