Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 1.00 |
| ▸ | TH | P07101 | 4/20 | 1.00 |
| ▸ | HTR1A | P08908 | 4/20 | 1.00 |
| ▸ | DRD3 | P35462 | 4/20 | 1.00 |
| ▸ | DRD1 | P21728 | 4/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | GMNN | O75496 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | GFER | P55789 | 2/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | RGS12 | O14924 | 1/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203698 | 1.00 | DRD2 (1.00) | DRD2THHTR1ADRD3DRD1 | |
| SCHEMBL1203699 | 1.00 | DRD2 (1.00) | DRD2THHTR1ADRD3DRD1 | |
| Hydrochloric Acid SCHEMBL10752801 | 0.99 | DRD2 (0.98) | DRD2THHTR1ADRD3DRD1 | |
| SCHEMBL15180898 | 0.93 | DRD2 (0.87) | DRD2THHTR1ADRD3DRD1 | |
| SCHEMBL1345058 | 0.90 | DRD2 (0.82) | DRD2THHTR1ADRD3DRD1 | |
| SCHEMBL1345853 | 0.90 | DRD2 (0.82) | DRD2THHTR1ADRD3DRD1 | |
| R-N-Propylnorapomorphine SCHEMBL13398114 | 0.90 | DRD2 (1.00) | DRD2THHTR1ADRD3DRD1 | |
| R-N-Propylnorapomorphine SCHEMBL13487203 | 0.90 | DRD2 (1.00) | DRD2THHTR1ADRD3DRD1 | |
| R-N-Propylnorapomorphine SCHEMBL29447877 | 0.90 | DRD2 (1.00) | DRD2THHTR1ADRD3DRD1 | |
| R-N-Propylnorapomorphine SCHEMBL249729 | 0.90 | DRD2 (1.00) | DRD2THHTR1ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687773-A | PSYCHOLOGICAL DISORDERS | MCLEAN HOSPITAL (US) | 1987-08-18 | — | — | US | claimed |
| US-4687773-A | PSYCHOLOGICAL DISORDERS | MCLEAN HOSPITAL (US) | 1987-08-18 | — | — | US | disclosed |