Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 1.00 |
| ▸ | DRD3 | P35462 | 5/20 | 1.00 |
| ▸ | TH | P07101 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | DRD1 | P21728 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | GMNN | O75496 | 2/20 | 1.00 |
| ▸ | GFER | P55789 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | RGS12 | O14924 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | THPO | P40225 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| R-N-Propylnorapomorphine SCHEMBL13487203 | 1.00 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| R-N-Propylnorapomorphine SCHEMBL29447877 | 1.00 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| R-N-Propylnorapomorphine SCHEMBL249729 | 1.00 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| R-N-Propylnorapomorphine SCHEMBL7997518 | 1.00 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| SCHEMBL14161595 | 0.91 | MAPT (0.83) | DRD2DRD3THMAPTMAPK1 | |
| SCHEMBL1203698 | 0.90 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| SCHEMBL10754712 | 0.90 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| SCHEMBL1203699 | 0.90 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| SCHEMBL19815875 | 0.89 | DRD2 (1.00) | DRD2DRD3THMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL10752801 | 0.88 | DRD2 (0.98) | DRD2DRD3THMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105949-A1 | RADIOSYNTHESIS OF ACID CHLORIDES | HAMMERSMITH IMANET LIMITED | 2010-04-29 | — | — | US | disclosed |
| US-7642375-B2 | Radiosynthesis of acid chlorides | HAMMERSMITH IMANET LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-20070287837-A1 | Radiosynthesis of Acid Chlorides | HAMMERSMITH IMANET LLIMITED (GB) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287837-A1 | Radiosynthesis of Acid Chlorides | HRAS, CLTC, CTH | DRD2 2095/4885DRD3 2838/4885TH 1185/4885 |
| US-20100105949-A1 | RADIOSYNTHESIS OF ACID CHLORIDES | HRAS, CLTC, CTH | DRD2 2095/4885DRD3 2838/4885TH 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.