SCHEMBL1075622

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1033853	0.83	NPC1 (0.52)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL1034332	0.83	SCN9A (0.49)	ALDH1A1MAPTTSHRHSD17B10HPGD
	SCHEMBL1033594	0.82	MAPT (0.62)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL1031951	0.82	SMN1; SMN2 (0.53)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL1034842	0.81	SIRT2 (0.51)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL1031934	0.80	EGLN1 (0.60)	ALDH1A1MAPTMEN1KMT2AKDM4E
	SCHEMBL1034077	0.80	RAB9A (0.53)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL1033355	0.80	SCD (0.61)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL1031321	0.80	ALDH1A1 (0.52)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL1034242	0.79	ALDH1A1 (0.54)	ALDH1A1NPC1RAB9APARP1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.