Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | PLEC | Q15149 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | ADH5 | P11766 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762279 | 0.80 | CYP3A4 (0.49) | CYP3A4BAZ2BHTTKMT2AHTR2A | |
| SCHEMBL10647207 | 0.77 | CYP3A4 (0.37) | CYP3A4BAZ2BHTTKMT2AHTR2A | |
| SCHEMBL14282012 | 0.73 | CYP11B1 (0.42) | CYP3A4BAZ2BHTTKMT2ALMNA | |
| SCHEMBL10645714 | 0.70 | CYP3A4 (0.36) | CYP3A4BAZ2BHTTKMT2AHTR2A | |
| SCHEMBL10647455 | 0.68 | TBXAS1 (0.37) | CYP3A4BAZ2BHTTKMT2AHTR2A | |
| SCHEMBL10365545 | 0.67 | CYP3A4 (0.47) | CYP3A4BAZ2BHTTKMT2AHTR2A | |
| SCHEMBL11000190 | 0.66 | CYP3A4 (0.56) | CYP3A4BAZ2BHTTKMT2AHTR2A | |
| SCHEMBL10648270 | 0.65 | TBXAS1 (0.40) | CYP3A4BAZ2BHTTKMT2AMAPT | |
| SCHEMBL11083639 | 0.65 | CTSL (0.35) | CYP3A4LMNAMAPK1MAPTL3MBTL1 | |
| SCHEMBL10645502 | 0.65 | STING1 (0.39) | CYP3A4BAZ2BHTTTBXAS1ADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699914-A | CONGESTIVE HEART FAILURE | A. NATTERMANN & CIE GMBH (DE) | 1987-10-13 | — | — | US | disclosed |