Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADH5 | P11766 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915280 | 0.83 | CYP3A4 (0.51) | CYP3A4BAZ2BKMT2ATDP1PLEC | |
| SCHEMBL10756776 | 0.80 | CYP3A4 (0.37) | CYP3A4BAZ2BKMT2ATDP1PLEC | |
| SCHEMBL11083639 | 0.79 | CTSL (0.35) | CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL11000190 | 0.77 | CYP3A4 (0.56) | CYP3A4BAZ2BKMT2ATDP1GFER | |
| SCHEMBL11005033 | 0.74 | BRD4 (0.45) | KMT2APOLBMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11009885 | 0.73 | CYP2D6 (0.42) | CYP3A4KMT2ATDP1ALDH1A1 | |
| SCHEMBL9364392 | 0.72 | LMNA (0.50) | CYP3A4BAZ2BKMT2ATDP1PLEC | |
| SCHEMBL27513743 | 0.72 | CYP3A4 (0.59) | CYP3A4BAZ2BKMT2ATDP1PLEC | |
| SCHEMBL29676040 | 0.70 | KMT2A (0.72) | CYP3A4BAZ2BKMT2ATDP1PLEC | |
| SCHEMBL6895118 | 0.70 | ENPP2 (0.59) | CYP3A4BAZ2BKMT2ATDP1PLEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699914-A | CONGESTIVE HEART FAILURE | A. NATTERMANN & CIE GMBH (DE) | 1987-10-13 | — | — | US | disclosed |