Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025531 | 0.71 | HTR1D (0.36) | DRD3DRD2HSD11B1HTR1DHTR1B | |
| SCHEMBL12337449 | 0.67 | GPR119 (0.45) | OPRM1 | |
| SCHEMBL7015754 | 0.67 | CHRNA7 (0.54) | DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL7015707 | 0.66 | CHRNA7 (0.52) | DRD3DRD2 | |
| SCHEMBL7389468 | 0.66 | MEN1 (0.42) | DRD3DRD2OPRM1OPRK1MEN1 | |
| SCHEMBL26452181 | 0.65 | PARP10 (0.58) | MEN1KMT2A | |
| SCHEMBL19616093 | 0.65 | OPRK1 (0.46) | OPRM1OPRK1MEN1KMT2A | |
| SCHEMBL12311988 | 0.65 | PLG (0.58) | DRD3DRD2OPRM1OPRK1ENPP2 | |
| SCHEMBL1791093 | 0.64 | HRH3 (0.64) | HRH3 | |
| SCHEMBL2278277 | 0.64 | HDAC6 (0.44) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274283-A1 | NOVEL N-SUBSTITUTED TETRAHYDROISOQUINOLINE/ISOINDOLINE HYDROXAMIC ACID COMPOUNDS | 4SC AG (DE) | 2011-01-19 | — | — | EP | disclosed |