Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 8/20 | 0.36 |
| ▸ | MLYCD | O95822 | 8/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758499 | 0.89 | MIF (0.42) | MIFMLYCDHTTCYP1A2CYP3A4 | |
| SCHEMBL10757347 | 0.89 | MIF (0.46) | MIFHTTHDAC6TSHR | |
| SCHEMBL20645845 | 0.74 | MIF (0.48) | MIFHTTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8642228 | 0.72 | F10 (0.33) | MIF | |
| SCHEMBL19899949 | 0.71 | MIF (0.38) | MIFMLYCDHTTCYP1A2CYP3A4 | |
| SCHEMBL8494420 | 0.70 | F10 (0.46) | MIFHTTTSHR | |
| SCHEMBL20645838 | 0.70 | MIF (0.50) | MIFHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20640879 | 0.70 | MIF (0.40) | MIFHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25061491 | 0.68 | MIF (0.35) | MIFMLYCDHTTCYP1A2CYP3A4 | |
| SCHEMBL25399266 | 0.68 | ALDH1A1 (0.44) | MIFMLYCDHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677114-A | REDUCING AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4677098-A | REDUCING AMNESIA AND TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |