Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756958 | 0.89 | MIF (0.36) | MIFHTTTSHRHDAC6 | |
| SCHEMBL10758499 | 0.89 | MIF (0.42) | MIFHTT | |
| SCHEMBL20645845 | 0.84 | MIF (0.48) | MIFHTT | |
| SCHEMBL20645838 | 0.81 | MIF (0.50) | MIFHTT | |
| SCHEMBL8494420 | 0.81 | F10 (0.46) | MIFHTTTSHR | |
| SCHEMBL20640544 | 0.77 | MIF (0.50) | MIFHTTTSHRTDP1L3MBTL1 | |
| SCHEMBL27526456 | 0.75 | HTT (0.48) | MIFHTTTSHRTDP1L3MBTL1 | |
| SCHEMBL20640879 | 0.74 | MIF (0.40) | MIFHTT | |
| SCHEMBL8444142 | 0.72 | MIF (0.58) | MIFHTTHDAC6 | |
| SCHEMBL12461336 | 0.71 | CYP4F2 (0.36) | MIFHTTTSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677114-A | REDUCING AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4677098-A | REDUCING AMNESIA AND TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |