Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441956 | 0.84 | ERN1 (0.49) | MEN1KMT2AALDH1A1RAB9AERN1 | |
| SCHEMBL2258945 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1RAB9AERN1 | |
| SCHEMBL10758156 | 0.74 | CYP2A6 (0.43) | MEN1KMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL9450944 | 0.74 | CYP1A2 (0.56) | MEN1KMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL2951665 | 0.73 | ERN1 (0.51) | MEN1KMT2AALDH1A1ERN1EGFR | |
| SCHEMBL10756969 | 0.73 | L3MBTL1 (0.45) | MEN1KMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL31083660 | 0.72 | KDM4E (0.51) | MEN1KMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL14615369 | 0.72 | MEN1 (0.47) | MEN1KMT2AEGFRTP53SMN1; SMN2 | |
| SCHEMBL6298830 | 0.71 | DHFR (0.45) | MEN1KMT2AALDH1A1RAB9AEGFR | |
| SCHEMBL12366048 | 0.71 | LMNA (0.42) | MEN1KMT2AALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4654352-A | AMINO SUBSTITUTED | PFIZER INC. (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0169012-A1 | Benzothiophene anti-diarrhoeal agents | Pfizer Limited (GB) | 1986-01-22 | — | — | EP | disclosed |