Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758736 | 0.89 | THRB (0.38) | NPC1ALDH1A1KDM4EMAPTCDK1 | |
| SCHEMBL10508148 | 0.86 | NPC1 (0.45) | NPC1ALDH1A1KDM4EMAPTCDK1 | |
| SCHEMBL7023958 | 0.83 | NPC1 (0.50) | NPC1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL10506658 | 0.81 | NPC1 (0.42) | NPC1ALDH1A1KDM4EMAPTCDK1 | |
| SCHEMBL11177162 | 0.79 | NPC1 (0.43) | NPC1ALDH1A1KDM4EMAPTCDK1 | |
| SCHEMBL7452390 | 0.79 | MAPT (0.49) | NPC1ALDH1A1KDM4EMAPTGAA | |
| Metsulfuron-Methyl SCHEMBL7576469 | 0.78 | NPC1 (0.46) | NPC1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL11184973 | 0.78 | ALDH1A1 (0.52) | NPC1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL11189126 | 0.78 | NPC1 (0.42) | NPC1ALDH1A1KDM4EMAPTGAA | |
| Metsulfuron-Methyl SCHEMBL21583 | 0.77 | NPC1 (0.46) | NPC1ALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659366-A | 2-(alkoximinoalkoxycarbonyl)-phenylsulphonylurea herbicides and fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |