SCHEMBL1075940

SCHEMBL1075940

CC1CCC(C(C)C)C(OC(=O)O)C1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.60
ALDH1A1 P00352 8/20 0.55
HPGD P15428 2/20 0.55
CYP19A1 P11511 2/20 0.53
TRPA1 O75762 2/20 0.48
TRPM8 Q7Z2W7 2/20 0.48
LMNA P02545 2/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
TSHR P16473 2/20 0.46
MAPT P10636 2/20 0.46
USP2 O75604 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13460327 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL13460250 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL5125214 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL16610788 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL28145617 0.98 EPHX1 (0.58) EPHX1ALDH1A1HPGDCYP19A1TRPA1
Ethylene Glycol SCHEMBL27579683 0.94 EPHX1 (0.55) EPHX1ALDH1A1HPGDCYP19A1TRPA1
Ethylene Glycol SCHEMBL28227214 0.94 EPHX1 (0.55) EPHX1ALDH1A1HPGDCYP19A1TRPA1
Ethylene Glycol SCHEMBL906564 0.94 EPHX1 (0.55) EPHX1ALDH1A1HPGDCYP19A1TRPA1
Bicarbonate SCHEMBL28880176 0.92 EPHX1 (0.53) EPHX1ALDH1A1HPGDCYP19A1LMNA
Propylene Glycol SCHEMBL906429 0.91 CYP19A1 (0.53) EPHX1ALDH1A1HPGDCYP19A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119015152-A Composition containing menthol carbonate precursor compound and use thereof 重庆医科大学 2024-11-26 CN claimed
CN-118812470-A Menthol carbonate precursor compound and synthesis method thereof 重庆医科大学 2024-10-22 CN claimed
CN-118496099-A Method for synthesizing menthyl carbonate compound through continuous flow 上海应用技术大学 2024-08-16 CN claimed
CN-112384077-B Solubilization of poorly soluble Cooling Material 西姆莱斯有限公司 2024-03-08 CN claimed
US-20240058243-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES SYMRISE AG (DE) 2024-02-22 US claimed
CN-117479843-A Composition for enhancing cooling effect 弗门尼舍公司 2024-01-30 CN claimed
US-11873605-B2 Liquid-state temporary reinforcing material, preparation method therefor and application thereof SHANGHAI UNIVERSITY (CN) 2024-01-16 US claimed
CN-117396589-A Oral care flavor and assessment method for improving pleasure status 奇华顿股份有限公司 2024-01-12 CN claimed
CN-117396588-A Oral care flavor and assessment method for improving state of agitation 奇华顿股份有限公司 2024-01-12 CN claimed
EP-4259287-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES Symrise AG (DE) 2023-10-18 EP claimed
WO-2009087578-A2 SENSATION MODIFYING TOPICAL COMPOSITION FOAM FOAMIX LTD. (IL) 2009-07-16 WO claimed
US-20080317923-A1 AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION SYMRISE GMBH & CO. KG (DE) 2008-12-25 US claimed
EP-1959915-A1 MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING Symrise GmbH & Co. KG (DE) 2008-08-27 EP claimed
EP-1958627-A2 Use of certain menthyl-3-oxocarbonic acid esters as physiological cooling agents Symrise GmbH & Co. KG (DE) 2008-08-20 EP claimed
US-20080175800-A1 USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2008-07-24 US claimed
WO-2007062957-A1 MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING SYMRISE GMBH & CO. KG (DE) 2007-06-07 WO claimed
CN-1796365-A Method for synthesizing amide of mint SHANGHAI PERFUME INST (CN) 2006-07-05 CN claimed
EP-0790883-B1 SKIN ENGAGING MEMBER GILLETTE CO (US) 1999-03-31 EP claimed
EP-0837760-A1 SHAVING AID COMPOSITE WITH AN INCLUSION COMPLEX OF A SKIN-SOOTHING AGENT AND CYCLODEXTRIN THE GILLETTE COMPANY (US) 1998-04-29 EP claimed
WO-1997002117-A1 SHAVING AID COMPOSITE WITH AN INCLUSION COMPLEX OF A SKIN-SOOTHING AGENT AND CYCLODEXTRIN THE GILLETTE COMPANY (US) 1997-01-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240058243-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES MGLL, GCDH, GK EPHX1 1246/4885ALDH1A1 935/4885HPGD 974/4885
US-20080175800-A1 USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES ECI1, OTC, MDH2 EPHX1 85/4885ALDH1A1 748/4885HPGD 135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.