Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10755808 | 0.81 | — | — | |
| SCHEMBL2433463 | 0.74 | DGAT1 (0.36) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL28750768 | 0.74 | DGAT1 (0.36) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL2433990 | 0.73 | DGAT1 (0.35) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL18921418 | 0.72 | CTSK (0.42) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL4948386 | 0.70 | DGAT1 (0.41) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL3163754 | 0.69 | HPGD (0.38) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL8563199 | 0.68 | CTSK (0.36) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL72410 | 0.68 | DGAT1 (0.38) | DGAT1HPGDCTSKUSP2SMN1; SMN2 | |
| SCHEMBL5430692 | 0.68 | CYP2B6 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677114-A | REDUCING AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4677098-A | REDUCING AMNESIA AND TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |