Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921418 | 0.72 | CTSK (0.42) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL4948386 | 0.70 | DGAT1 (0.41) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL2433463 | 0.70 | DGAT1 (0.36) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL28750768 | 0.70 | DGAT1 (0.36) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL3163754 | 0.69 | HPGD (0.38) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL2433990 | 0.69 | DGAT1 (0.35) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL10760132 | 0.68 | DGAT1 (0.34) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL72410 | 0.68 | DGAT1 (0.38) | CTSKDGAT1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL12503127 | 0.68 | DGAT1 (0.44) | DGAT1USP2SMN1; SMN2 | |
| SCHEMBL8487930 | 0.67 | DGAT1 (0.40) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559752-B1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5157128-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-10-20 | — | — | US | disclosed |