Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764372 | 0.83 | PTGS2 (0.60) | PDE3BPDE3APTGS1PTGS2GPR119 | |
| SCHEMBL10764678 | 0.83 | PDE3B (0.43) | PDE3BPDE3APTGS1PTGS2KMT2A | |
| SCHEMBL10764444 | 0.80 | HSD17B10 (0.40) | PDE3BPDE3APTGS1PTGS2HSD17B10 | |
| SCHEMBL10760541 | 0.80 | PDE3B (0.56) | PDE3BPDE3AHPGDTSHRALDH1A1 | |
| SCHEMBL10761951 | 0.78 | NPC1 (0.48) | PDE3BPDE3APTGS1PTGS2KMT2A | |
| SCHEMBL10763296 | 0.78 | PDE3A (0.43) | PDE3BPDE3APTGS1PTGS2TSHR | |
| SCHEMBL10765623 | 0.77 | PDE3A (0.43) | PDE3BPDE3APTGS1PTGS2KMT2A | |
| SCHEMBL10763618 | 0.77 | PTGS2 (0.67) | PDE3BPDE3APTGS1PTGS2HSD17B10 | |
| SCHEMBL10763206 | 0.76 | PDE3A (0.42) | PDE3BPDE3APTGS1PTGS2MAPK1 | |
| SCHEMBL10762546 | 0.76 | PDE3B (0.50) | PDE3BPDE3APTGS1PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |