SCHEMBL10760587

SCHEMBL10760587

CCOC(=O)C(=N\OC)/C(N)=N/O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
CYP1A2 P05177 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 4/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
ALDH1A1 P00352 6/20 0.33
HTT P42858 1/20 0.33
ABCB1 P08183 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
GLO1 Q04760 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10760592 1.00 ALOX15 (0.39) ALOX15CYP1A2MEN1KMT2AMAPT
SCHEMBL11144723 0.85 ALOX15 (0.44) ALOX15CYP1A2MEN1KMT2AMAPT
SCHEMBL10352005 0.83 ALOX15 (0.43) ALOX15CYP1A2MEN1KMT2AMAPT
SCHEMBL4836138 0.82 ALDH1A1 (0.42) ALOX15MEN1KMT2AMAPTALDH1A1
Hydrochloric Acid SCHEMBL8570887 0.79
SCHEMBL20878527 0.79 ALOX15 (0.46) ALOX15CYP1A2MEN1KMT2AMAPT
SCHEMBL641538 0.78
SCHEMBL641537 0.78
SCHEMBL3222024 0.78
SCHEMBL9076933 0.77 GLO1 (0.45) ALOX15MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0244637-A1 Starting compounds for 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-11-11 EP disclosed
EP-0123024-A2 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-31 EP disclosed
EP-0030630-A2 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-06-24 EP disclosed