Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766800 | 0.91 | PTGS1 (0.54) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10765726 | 0.81 | RAB9A (0.55) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10766427 | 0.80 | PTGS1 (0.59) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10764037 | 0.77 | PTGS2 (0.54) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10761669 | 0.72 | ALDH1A1 (0.31) | MAPTALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL10765472 | 0.71 | SMN1; SMN2 (0.62) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10763237 | 0.71 | PTGS1 (0.56) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10761718 | 0.69 | RAB9A (0.73) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10763874 | 0.69 | RAB9A (0.66) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10761723 | 0.69 | RAB9A (0.62) | PTGS1PTGS2RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |