SCHEMBL10761995

SCHEMBL10761995

CC(=O)N1C(=O)CC[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 9/20 0.50
F2 P00734 2/20 0.49
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.45
ELANE P08246 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6473564 0.90 FKBP1A (0.50) FKBP1AF2HPGDTSHR
SCHEMBL30882647 0.90 FKBP1A (0.50) FKBP1AF2HPGDTSHR
SCHEMBL18948763 0.88 FKBP1A (0.52) FKBP1AF2HPGD
SCHEMBL10760886 0.87 FOLH1 (0.52) FKBP1AF2HPGD
SCHEMBL12890921 0.85 KLK7 (0.49) FKBP1AF2HPGD
SCHEMBL1300740 0.85 KLK7 (0.49) FKBP1AF2HPGD
SCHEMBL842288 0.85 KLK7 (0.49) FKBP1AF2HPGD
SCHEMBL14299314 0.85 FKBP1A (0.50) FKBP1AF2ALDH1A1HPGDTSHR
SCHEMBL13385271 0.85 FKBP1A (0.50) FKBP1AF2ALDH1A1HPGDTSHR
SCHEMBL28387613 0.85 ELANE (0.48) FKBP1AHPGDELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4661512-A Adamantanamine derivatives, processes for their preparation and drugs in which they are present S. A. PANMEDICA (FR) 1987-04-28 US disclosed