Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12890921 | 1.00 | KLK7 (0.49) | KLK7FKBP1AF2HPGDPARP1 | |
| SCHEMBL842288 | 1.00 | KLK7 (0.49) | KLK7FKBP1AF2HPGDPARP1 | |
| SCHEMBL13601195 | 0.93 | FKBP1A (0.52) | KLK7FKBP1AF2HPGDPARP1 | |
| SCHEMBL7420306 | 0.91 | KLK7 (0.47) | KLK7FKBP1AF2HPGDPARP1 | |
| SCHEMBL9951077 | 0.91 | KLK7 (0.47) | KLK7FKBP1AF2HPGDPARP1 | |
| SCHEMBL31390581 | 0.89 | FKBP1A (0.48) | KLK7FKBP1AF2HPGDPARP1 | |
| SCHEMBL18948763 | 0.87 | FKBP1A (0.52) | FKBP1AF2HPGD | |
| SCHEMBL28816407 | 0.86 | STS (0.44) | KLK7FKBP1APARP1CTSL | |
| SCHEMBL27996466 | 0.86 | STS (0.44) | KLK7FKBP1APARP1CTSL | |
| SCHEMBL10761995 | 0.85 | FKBP1A (0.50) | FKBP1AF2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249291-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | CASMA THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| US-11542492-B2 | Ligand-directed covalent modification of protein | CELGENE CAR LLC (BM) | 2023-01-03 | — | — | US | disclosed |
| CN-108619141-B | Antibacterial composition and application thereof | 山东轩竹医药科技有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-108778270-B | Antibacterial composition and application thereof | 吉林四环制药有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-107531709-B | Beta-lactamase inhibitor and use thereof | 吉林四环制药有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-108822014-B | Synthetic method of avibactam intermediate | 珠海联邦制药股份有限公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-109721522-A | A kind of high-quality N- tertbutyloxycarbonyl-L-Glutimic acid benzyl ester industrialized preparing process | 常州吉恩药业有限公司 | 2019-05-07 | — | — | CN | disclosed |
| US-10167283-B2 | β-lactamase inhibitors and uses thereof | SUANZHU PHARMA CO., LTD. (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-05-31 | — | — | US | disclosed |
| US-7498330-B2 | 4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds | LES LABORATORIES SERVIER (FR) | 2009-03-03 | — | — | US | disclosed |
| EP-1935885-A2 | Melanin concentrating hormone receptor ligands : substituted 1-benzyl-4-aryl piperazine analogues. | NEUROGEN CORPORATION (US) | 2008-06-25 | — | — | EP | disclosed |
| US-7241765-B2 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | NEUROGEN CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060229298-A1 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | HUTCHISON ALAN | 2006-10-12 | — | — | US | disclosed |
| US-7081458-B2 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | NEUROGEN CORP. (US) | 2006-07-25 | — | — | US | disclosed |
| US-20050209234-A1 | 4-Oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds | LES LABORATOIRES SERVIER (FR) | 2005-09-22 | — | — | US | disclosed |
| US-20050182068-A1 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | HUTCHISON ALAN (US) | 2005-08-18 | — | — | US | disclosed |
| US-20050065162-A1 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION | 2005-03-24 | — | — | US | disclosed |
| EP-1389189-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094799-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229298-A1 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | MCHR1, MCHR2, MC1R | KLK7 3087/4885FKBP1A 2345/4885F2 4667/4885 |
| US-11542492-B2 | Ligand-directed covalent modification of protein | PTMS, SPR, DNPEP | KLK7 1646/4885FKBP1A 617/4885F2 1146/4885 |
| US-10167283-B2 | β-lactamase inhibitors and uses thereof | MGAM, LCT, ALPI | KLK7 1686/4885FKBP1A 2368/4885F2 1477/4885 |
| US-20050209234-A1 | 4-Oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds | F2, TBXA2R, PDGFRA | KLK7 3030/4885FKBP1A 1720/4885F2 1/4885 |
| US-20050065162-A1 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | MCHR1, MCHR2, MC1R | KLK7 3087/4885FKBP1A 2345/4885F2 4667/4885 |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | MGAM, LCT, ALPI | KLK7 1594/4885FKBP1A 2329/4885F2 1413/4885 |
| US-20050182068-A1 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | MCHR1, MCHR2, MC1R | KLK7 3087/4885FKBP1A 2345/4885F2 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.