SCHEMBL842288

SCHEMBL842288

CC(C)(C)OC(=O)N1C(=O)CC[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 2/20 0.49
FKBP1A P62942 7/20 0.48
F2 P00734 1/20 0.44
HPGD P15428 1/20 0.44
PARP1 P09874 1/20 0.42
CTSL P07711 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12890921 1.00 KLK7 (0.49) KLK7FKBP1AF2HPGDPARP1
SCHEMBL1300740 1.00 KLK7 (0.49) KLK7FKBP1AF2HPGDPARP1
SCHEMBL13601195 0.93 FKBP1A (0.52) KLK7FKBP1AF2HPGDPARP1
SCHEMBL7420306 0.91 KLK7 (0.47) KLK7FKBP1AF2HPGDPARP1
SCHEMBL9951077 0.91 KLK7 (0.47) KLK7FKBP1AF2HPGDPARP1
SCHEMBL31390581 0.89 FKBP1A (0.48) KLK7FKBP1AF2HPGDPARP1
SCHEMBL18948763 0.87 FKBP1A (0.52) FKBP1AF2HPGD
SCHEMBL28816407 0.86 STS (0.44) KLK7FKBP1APARP1CTSL
SCHEMBL27996466 0.86 STS (0.44) KLK7FKBP1APARP1CTSL
SCHEMBL10761995 0.85 FKBP1A (0.50) FKBP1AF2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480463-A Synthetic method and preparation device of natural amino acid derivative 黄淮学院 2021-10-08 CN claimed
CN-109912499-B Abamebactam intermediate and preparation method thereof 江苏奥赛康药业有限公司 2021-04-27 CN claimed
EP-4727546-A2 PROTEOSOME COMPLEX INHIBITORS TARGETING CLPP1P2 PROTEASE The Global Alliance for TB Drug Development, Inc. (US) 2026-04-22 EP disclosed
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2025-07-24 US disclosed
US-20250122225-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-04-17 US disclosed
WO-2025019626-A2 PROTEOSOME COMPLEX INHIBITORS TARGETING CLPP1P2 PROTEASE THE GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT, INC. (US) 2025-01-23 WO disclosed
US-20240382624-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED DYES THEIR RELATED USES ON TARGET LABORATORIES INC (US) 2024-11-21 US disclosed
US-20240299590-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED DYES THEIR RELATED USES ON TARGET LABORATORIES INC (US) 2024-09-12 US disclosed
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION 2024-07-18 US disclosed
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION 2024-07-18 US disclosed
EP-4351663-A1 TRISLINKER-CONJUGATED DIMERIC LABELLING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2024-04-17 EP disclosed
EP-1346982-A1 VLA-4 INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-09-24 EP disclosed
WO-2002094799-A2 MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES NEUROGEN CORPORATION (US) 2002-11-28 WO disclosed
EP-0826663-B1 Alkynylamino acid derivatives and their use as pharmaceutical compounds LILLY CO ELI (GB) 2001-10-31 EP disclosed
US-6143715-A FOR TREATING AND PREVENTION OF HEPATITIS C VIURS INFECTIONS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2000-11-07 US disclosed
EP-1012180-A2 HEPATITIS C INHIBITOR PEPTIDE ANALOGUES BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2000-06-28 EP disclosed
EP-1003775-A2 HEPATITIS C INHIBITOR PEPTIDES BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2000-05-31 EP disclosed
WO-1999007733-A2 HEPATITIS C INHIBITOR PEPTIDES BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1999-02-18 WO disclosed
WO-1999007734-A2 HEPATITIS C INHIBITOR PEPTIDE ANALOGUES BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1999-02-18 WO disclosed
EP-0826663-A2 Alkynylamino acid derivatives and their use as pharmaceutical compounds ELI LILLY AND COMPANY LIMITED (GB) 1998-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240382624-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED DYES THEIR RELATED USES FAP, FIBP, IK KLK7 1696/4885FKBP1A 823/4885F2 458/4885
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF FAP, FIBP, FGFR1 KLK7 1770/4885FKBP1A 1257/4885F2 1262/4885
US-20240299590-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED DYES THEIR RELATED USES FAP, FIBP, IK KLK7 1696/4885FKBP1A 823/4885F2 458/4885
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM TK1, TK2, TMT1A KLK7 2482/4885FKBP1A 782/4885F2 971/4885
US-20250122225-A1 MASP-2 INHIBITORS AND METHODS OF USE MASP2, SPINT2, SERPINB1 KLK7 170/4885FKBP1A 4076/4885F2 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.