Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882647 | 1.00 | FKBP1A (0.50) | FKBP1AF2HPGDNPC1RAB9A | |
| SCHEMBL10761995 | 0.90 | FKBP1A (0.50) | FKBP1AF2HPGDTSHR | |
| SCHEMBL10760886 | 0.88 | FOLH1 (0.52) | FKBP1AF2HPGD | |
| SCHEMBL18948763 | 0.87 | FKBP1A (0.52) | FKBP1AF2HPGDNPC1RAB9A | |
| SCHEMBL12890921 | 0.84 | KLK7 (0.49) | FKBP1AF2HPGDKLK7 | |
| SCHEMBL1300740 | 0.84 | KLK7 (0.49) | FKBP1AF2HPGDKLK7 | |
| SCHEMBL842288 | 0.84 | KLK7 (0.49) | FKBP1AF2HPGDKLK7 | |
| SCHEMBL21869824 | 0.83 | FKBP1A (0.53) | FKBP1A | |
| SCHEMBL28663248 | 0.83 | FKBP1A (0.53) | FKBP1A | |
| SCHEMBL14299314 | 0.83 | FKBP1A (0.50) | FKBP1AF2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953801-B2 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues | NEUROGEN CORPORATION (US) | 2005-10-11 | — | — | US | disclosed |