Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647585 | 0.83 | MAPT (0.50) | ALDH1A1GAARAB9AKMT2ALMNA | |
| SCHEMBL27951738 | 0.83 | MAPT (0.70) | ALDH1A1GAARAB9ANPC1TDP1 | |
| SCHEMBL14602517 | 0.83 | LMNA (0.55) | ALDH1A1GAARAB9ANPC1TDP1 | |
| SCHEMBL9402939 | 0.83 | CA1 (0.59) | ALDH1A1GAARAB9ANPC1KMT2A | |
| SCHEMBL23921253 | 0.83 | ALDH1A1 (0.61) | ALDH1A1GAARAB9ANPC1TDP1 | |
| SCHEMBL8638149 | 0.81 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1TDP1KMT2A | |
| SCHEMBL8547880 | 0.81 | RAB9A (0.56) | GAARAB9ANPC1HDAC1HDAC6 | |
| SCHEMBL10763261 | 0.81 | MAPT (0.47) | ALDH1A1GAARAB9ANPC1KMT2A | |
| SCHEMBL27916996 | 0.81 | OGG1 (0.61) | ALDH1A1GAARAB9ANPC1HDAC1 | |
| SCHEMBL5592540 | 0.81 | MAPT (0.47) | ALDH1A1GAARAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735756-B | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |
| CN-113149868-B | Method for synthesizing axichiral diene compound by trivalent rhodium catalysis | 陕西师范大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115433222-A | Preparation method and application of 2- (gem-difluoropropylene) benzamide compound | 五邑大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-115368272-A | Preparation method of 4-cyano-2-methoxybenzaldehyde | 汉瑞药业(荆门)有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-113735756-A | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113149868-A | Method for synthesizing axial chiral allene compound by using trivalent rhodium as catalyst | 陕西师范大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-110305062-B | Substituted isoquinolone compound and synthesis method and application thereof | 广州医科大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-107082761-B | Phenanthridinone or benzophenanthridinone derivative and synthesis method thereof | 上海大学 | 2020-04-03 | — | — | CN | disclosed |
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090029990-A1 | Dihydropteridinones in the treatment of respiratory diseases | MAIER UDO | 2009-01-29 | — | — | US | disclosed |
| WO-2009001132-A1 | PYRAZINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF LUNG DISEASES | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-20 | — | — | US | disclosed |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-20 | — | — | US | disclosed |
| WO-2007075468-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070043055-A1 | Dihydropteridinones in the treatment of respiratory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-6576765-B2 | Process for preparing amic acid esters | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| US-20030032667-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-02-13 | — | — | US | disclosed |
| EP-1182199-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043055-A1 | Dihydropteridinones in the treatment of respiratory diseases | QDPR, DHPS, NDUFS6 | ALDH1A1 1078/4885GAA 2532/4885RAB9A 2056/4885 |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | IL2, IRF3, EIF2AK2 | ALDH1A1 1178/4885GAA 1064/4885RAB9A 2097/4885 |
| US-20030032667-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | MCCC2, EMC1, GANC | ALDH1A1 651/4885GAA 853/4885RAB9A 774/4885 |
| US-20090029990-A1 | Dihydropteridinones in the treatment of respiratory diseases | QDPR, DHPS, NDUFS6 | ALDH1A1 1078/4885GAA 2532/4885RAB9A 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.