Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156203 | 0.69 | CYP1A2 (0.34) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL28312403 | 0.68 | ALDH1A1 (0.40) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL7789826 | 0.67 | GSK3A (0.41) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL6713101 | 0.66 | MAOA (0.48) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL28858304 | 0.65 | LOX (0.35) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL9835334 | 0.64 | MAOA (0.47) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL11333917 | 0.64 | GAA (0.40) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL8995349 | 0.63 | LOX (0.38) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL28327185 | 0.63 | LOX (0.38) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL28200356 | 0.62 | LOX (0.37) | LOXLOXL3LOXL4LOXL2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4697018-A | CARBONLESS DUPLICATION OR THERMAL MARKING DYES | THE HILTON-DAVIS CHEMICAL CO. (US) | 1987-09-29 | — | — | US | disclosed |
| US-4558137-A | CHROMAGENS, PRESSURE AND HEAT SENSITIVE CARBONLESS DUPLICATING SYSTEMS | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4403791-A | Carbonless duplicating and marking systems | STERLING DRUG INC. (US) | 1983-09-13 | — | — | US | disclosed |