Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763322 | 0.69 | LOX (0.40) | SMN1; SMN2USP2ALDH1A1POLBMAPT | |
| SCHEMBL28858304 | 0.65 | LOX (0.35) | MAPK1SMN1; SMN2USP2ALDH1A1POLB | |
| SCHEMBL11700274 | 0.62 | PTGS2 (0.33) | CYP1A2SMN1; SMN2MAPTBCHEPTGS2 | |
| SCHEMBL21485070 | 0.59 | MAPK1 (0.33) | MAPK1SMN1; SMN2ALDH1A1LOXLOXL3 | |
| SCHEMBL7789826 | 0.59 | GSK3A (0.41) | CYP1A2MAPK1CYP2C19SMN1; SMN2USP2 | |
| SCHEMBL3146322 | 0.58 | LOX (0.33) | LOXLOXL3LOXL4LOXL2GSK3A | |
| SCHEMBL979712 | 0.57 | L3MBTL1 (0.39) | MAPK1SMN1; SMN2USP2ALDH1A1POLB | |
| SCHEMBL28902166 | 0.57 | L3MBTL1 (0.39) | MAPK1SMN1; SMN2USP2ALDH1A1POLB | |
| SCHEMBL6713101 | 0.57 | MAOA (0.48) | CYP1A2CYP2C19SMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL9835334 | 0.56 | MAOA (0.47) | CYP1A2CYP2C19SMN1; SMN2USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180355402-A1 | DIAGNOSTIC STRIP FOR DETERMINING THE AMOUNT OF SARCOSINE, CREATININE AND HYDROGEN PEROXIDE IN A BIOLOGICAL OR ENVIRONMENTAL SAMPLE | Prevention Medicals s.r.o. (CZ) | 2018-12-13 | — | — | US | claimed |
| EP-3404418-A2 | A DIAGNOSTIC STRIP FOR DETERMINING THE AMOUNT OF SARCOSINE, CREATININE AND HYDROGEN PEROXIDE IN A BIOLOGICAL OR ENVIRONMENTAL SAMPLE | Prevention Medicals s.r.o. (CZ) | 2018-11-21 | — | — | EP | claimed |
| EP-3404418-A3 | A DIAGNOSTIC STRIP FOR DETERMINING THE AMOUNT OF SARCOSINE, CREATININE AND HYDROGEN PEROXIDE IN A BIOLOGICAL OR ENVIRONMENTAL SAMPLE | Prevention Medicals s.r.o. (CZ) | 2018-12-19 | — | — | EP | disclosed |
| US-20180355402-A1 | DIAGNOSTIC STRIP FOR DETERMINING THE AMOUNT OF SARCOSINE, CREATININE AND HYDROGEN PEROXIDE IN A BIOLOGICAL OR ENVIRONMENTAL SAMPLE | Prevention Medicals s.r.o. (CZ) | 2018-12-13 | — | — | US | disclosed |
| US-20180355402-A1 | DIAGNOSTIC STRIP FOR DETERMINING THE AMOUNT OF SARCOSINE, CREATININE AND HYDROGEN PEROXIDE IN A BIOLOGICAL OR ENVIRONMENTAL SAMPLE | Prevention Medicals s.r.o. (CZ) | 2018-12-13 | — | — | US | disclosed |
| EP-3404418-A2 | A DIAGNOSTIC STRIP FOR DETERMINING THE AMOUNT OF SARCOSINE, CREATININE AND HYDROGEN PEROXIDE IN A BIOLOGICAL OR ENVIRONMENTAL SAMPLE | Prevention Medicals s.r.o. (CZ) | 2018-11-21 | — | — | EP | disclosed |
| EP-3404418-A2 | A DIAGNOSTIC STRIP FOR DETERMINING THE AMOUNT OF SARCOSINE, CREATININE AND HYDROGEN PEROXIDE IN A BIOLOGICAL OR ENVIRONMENTAL SAMPLE | Prevention Medicals s.r.o. (CZ) | 2018-11-21 | — | — | EP | disclosed |
| US-7705050-B2 | Amides, useful in the inhibition of IL-8-induced chemotaxis of neutrophils | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2010-04-27 | — | — | US | disclosed |
| EP-1255726-B1 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-11-11 | — | — | EP | disclosed |
| US-20040181073-A1 | Amides, useful in the inhibition of il-8-induced chemotaxis of neutrophils | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181073-A1 | Amides, useful in the inhibition of il-8-induced chemotaxis of neutrophils | CXCL8, MMP8, CCR8 | CYP1A2 569/4885MAPK1 2258/4885CYP2C19 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.