Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 9/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762847 | 0.86 | GPR119 (0.43) | KDM4ESMN1; SMN2RAB9AALDH1A1PDE3B | |
| SCHEMBL10763162 | 0.84 | GPR119 (0.41) | KDM4ESMN1; SMN2RAB9ALMNAALDH1A1 | |
| SCHEMBL10761023 | 0.83 | MAOB (0.44) | KDM4ESMN1; SMN2RAB9ALMNAALDH1A1 | |
| SCHEMBL10760273 | 0.82 | PDE3B (0.42) | KDM4ESMN1; SMN2LMNAALDH1A1PDE3B | |
| SCHEMBL10760965 | 0.81 | PDE3B (0.41) | PDE3BPDE3A | |
| SCHEMBL10765826 | 0.81 | PDE3A (0.36) | KDM4ESMN1; SMN2RAB9ALMNAL3MBTL1 | |
| SCHEMBL10764750 | 0.81 | PDE3B (0.41) | ALDH1A1PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10765848 | 0.80 | PDE3A (0.35) | KDM4ESMN1; SMN2RAB9ALMNAL3MBTL1 | |
| SCHEMBL10767498 | 0.80 | GPR119 (0.41) | KDM4ESMN1; SMN2RAB9ALMNAL3MBTL1 | |
| SCHEMBL10765555 | 0.80 | PDE3A (0.42) | KDM4ESMN1; SMN2ALDH1A1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |