Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.71 |
| ▸ | DRD3 | P35462 | 5/20 | 0.71 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395544 | 0.90 | DRD2 (0.71) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL11009077 | 0.88 | DRD2 (0.67) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL10394949 | 0.86 | DRD2 (0.69) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL8394614 | 0.83 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL2701521 | 0.83 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL2702018 | 0.83 | DRD2 (1.00) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL11008652 | 0.82 | ACHE (0.62) | DRD2DRD3MTNR1AMTNR1BACHE | |
| Hydrochloric Acid SCHEMBL6339640 | 0.82 | DRD2 (0.97) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL6404851 | 0.81 | POLB (0.76) | DRD2DRD3MTNR1AMTNR1BACHE | |
| SCHEMBL6404849 | 0.81 | POLB (0.76) | DRD2DRD3MTNR1AMTNR1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213080-A2 | Hydrogenated pyridine derivatives | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | claimed |