SCHEMBL1076558

SCHEMBL1076558

C=CCC(=CN)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.40
MAOB P27338 4/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
AKT1 P31749 1/20 0.39
HDAC3 O15379 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11673299 0.81 AKT1 (0.40) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL9596280 0.81 AKT1 (0.40) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL1076032 0.81 AKT1 (0.40) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL11673293 0.81 AKT1 (0.40) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL6438770 0.79 AKT1 (0.39) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL727277 0.79 AKT1 (0.39) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL476634 0.79 MAOA (0.53) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL11048295 0.79 AKT1 (0.39) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL9723351 0.79 AKT1 (0.39) MAOAMAOBHDAC1HDAC2AKT1
SCHEMBL11048275 0.79 AKT1 (0.39) MAOAMAOBHDAC1HDAC2AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423777-B Resin composition for optical material, optical film and display device DIC株式会社 2023-03-24 CN claimed
CN-114539459-A Solid-phase synthesis carrier and preparation method and application thereof 西安蓝晓科技新材料股份有限公司 2022-05-27 CN claimed
CN-114539458-A Porous resin applied to solid phase synthesis and preparation method thereof 西安蓝晓科技新材料股份有限公司 2022-05-27 CN claimed
CN-113423777-A Resin composition for optical material, optical film and display device DIC株式会社 2021-09-21 CN claimed
WO-2020162259-A1 RESIN COMPOSITION FOR OPTICAL MATERIAL, OPTICAL FILM, AND DISPLAY DEVICE DIC株式会社 2020-08-13 WO claimed
US-8802745-B2 Porous resin bead and method for producing nucleic acid using the same NITTO DENKO CORPORATION (JP) 2014-08-12 US claimed
US-8653152-B2 Porous resin bead and method for producing nucleic acid using the same NITTO DENKO CORPORATION (JP) 2014-02-18 US claimed
EP-1081492-B1 PACKING MATERIAL FOR CHROMATOGRAPHY HAVING NOVEL CHARACTERISTIC AND METHOD FOR ISOLATION OF SUBSTANCE USING THE SAME CELLSEED INC (JP) 2009-01-14 EP claimed
US-5391667-A Blend with ethynically unsaturated monomer having atleast one amine or amine-displaceable functionality and crosslinking agent; supports ISIS PHARMACEUTICALS (US) 1995-02-21 US claimed
US-12037422-B2 Gel material NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2024-07-16 US disclosed
CN-114539458-B Porous resin applied to solid phase synthesis and preparation method thereof 西安蓝晓科技新材料股份有限公司 2023-07-25 CN disclosed
CN-114539459-B Solid phase synthesis carrier and preparation method and application thereof 西安蓝晓科技新材料股份有限公司 2023-07-25 CN disclosed
US-11643389-B2 Method for producing maleimide compound, compound and solid resin TOKYO OHKA KOGYO CO., LTD. (JP) 2023-05-09 US disclosed
US-11371015-B2 Graft polymer, temperature-responsive substrate for cell culture using the same and production method therefor, as well as liquid chromatographic carrier having the novel graft polymer immomibilized thereon and liquid chromatographic method using the same Sakai, Hideaki (JP) 2022-06-28 US disclosed
EP-0400705-A1 Filling material composition STAMICARBON B.V. (NL) 1990-12-05 EP disclosed
EP-0366190-A1 Bismaleimide compositions DSM N.V. (NL) 1990-05-02 EP disclosed
EP-0334422-A2 Spherical particles STAMICARBON B.V. (NL) 1989-09-27 EP disclosed
EP-0293112-A2 Resin composition and electrical laminate obtained therefrom Hitachi Chemical Co., Ltd. (JP) 1988-11-30 EP disclosed
US-4473630-A Liquid developer comprising aminoalkyl styrene polymer for electrostatic images FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4097420-A Method for preparation of macroporous amphoteric ion exchangers with highly crosslinked hydrophilic polymeric matrix CESKOSLOVENSKA AKADEMIE VED (CS) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11643389-B2 Method for producing maleimide compound, compound and solid resin DAP3, MEP1A, ASS1 MAOA 3088/4885MAOB 3790/4885HDAC1 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.