Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768907 | 0.82 | MGAM (0.38) | HTTLMNAKDM5AKDM2BKDM4C | |
| SCHEMBL31172566 | 0.82 | HTT (0.49) | HTTLMNAKDM5AKDM2BKDM4C | |
| SCHEMBL10764140 | 0.78 | HDAC1 (0.41) | HDAC1HDAC6MEN1TSHRKMT2A | |
| SCHEMBL10770003 | 0.75 | TBXAS1 (0.50) | LMNAMEN1KMT2A | |
| SCHEMBL19857480 | 0.74 | GABRP (0.46) | MEN1KMT2AMAPTSLC22A12MGAM | |
| SCHEMBL10768873 | 0.74 | MGAM (0.35) | LMNAKDM5AKDM4CKDM5BMEN1 | |
| SCHEMBL7081878 | 0.73 | HTT (0.75) | HTTKDM5AKDM2BKDM4CKDM5B | |
| Oxalic Acid SCHEMBL10766927 | 0.73 | TBXAS1 (0.48) | LMNAMEN1KMT2A | |
| SCHEMBL10764581 | 0.72 | HCAR2 (0.41) | LMNAMEN1KMT2AMAPTMGAM | |
| SCHEMBL10447248 | 0.71 | MGAM (0.38) | LMNAKDM5AKDM4CKDM5BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | claimed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | disclosed |