Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768907 | 0.84 | MGAM (0.38) | MGAMSLC22A12P4HA1P4HTMKDM5A | |
| SCHEMBL10770003 | 0.82 | TBXAS1 (0.50) | TBXAS1MEN1LMNAKMT2A | |
| Oxalic Acid SCHEMBL10766927 | 0.80 | TBXAS1 (0.48) | TBXAS1MEN1LMNAKMT2A | |
| SCHEMBL10764140 | 0.77 | HDAC1 (0.41) | MEN1KMT2AHSD17B10 | |
| SCHEMBL10764581 | 0.76 | HCAR2 (0.41) | MGAMP4HA1P4HTMPOLBMIF | |
| SCHEMBL19857480 | 0.75 | GABRP (0.46) | MGAMSLC22A12P4HA1P4HTMPOLB | |
| SCHEMBL9037560 | 0.75 | HCAR2 (0.40) | MGAMP4HA1P4HTMPOLBMIF | |
| SCHEMBL10766358 | 0.74 | HTT (0.53) | MGAMSLC22A12KDM5AKDM4CKDM5B | |
| SCHEMBL29819483 | 0.72 | TSHR (0.44) | MGAMP4HA1P4HTMMIFHCAR3 | |
| SCHEMBL10447248 | 0.72 | MGAM (0.38) | MGAMP4HA1P4HTMPOLBKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | claimed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | disclosed |