Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | DDT | P30046 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768873 | 0.84 | MGAM (0.35) | MGAMSLC22A12LMNAP4HA1P4HTM | |
| SCHEMBL10766358 | 0.82 | HTT (0.53) | MGAMSLC22A12HTTLMNAHDAC1 | |
| SCHEMBL10770003 | 0.82 | TBXAS1 (0.50) | LMNA | |
| Oxalic Acid SCHEMBL10766927 | 0.80 | TBXAS1 (0.48) | LMNA | |
| SCHEMBL10764581 | 0.76 | HCAR2 (0.41) | MGAMLMNAPSMD14P4HA1P4HTM | |
| SCHEMBL19857480 | 0.75 | GABRP (0.46) | MGAMSLC22A12P4HA1P4HTMKDM4E | |
| SCHEMBL9037560 | 0.75 | HCAR2 (0.40) | MGAMLMNAPSMD14P4HA1P4HTM | |
| SCHEMBL10764140 | 0.74 | HDAC1 (0.41) | HDAC1HDAC6 | |
| SCHEMBL10447248 | 0.72 | MGAM (0.38) | MGAMLMNAPSMD14P4HA1P4HTM | |
| SCHEMBL29819483 | 0.72 | TSHR (0.44) | MGAMP4HA1P4HTMDDTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | claimed |