Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310013 | 0.78 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL10762748 | 0.78 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL4457363 | 0.71 | TDP1 (0.61) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL9354185 | 0.71 | ALDH1A1 (0.40) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL11695120 | 0.70 | TDP1 (0.41) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL9614598 | 0.70 | TDP1 (0.48) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL10695742 | 0.68 | GAA (0.42) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL66892 | 0.68 | TDP1 (1.00) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL7259791 | 0.67 | TDP1 (0.56) | TDP1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL8965844 | 0.67 | TDP1 (0.56) | TDP1ALDH1A1TSHRLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125621-B1 | ONE POT PROCESS FOR THE PREPARATION OF N-ALKYL-ANILINES SUBSTITUTED IN THE NUCLEUS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |
| US-4540816-A | Single-vessel process for preparing ring-substituted n-alkylanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0125621-A1 | One pot process for the preparation of N-alkyl-anilines substituted in the nucleus | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | disclosed |