Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762748 | 0.81 | ALDH1A1 (0.50) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL12310013 | 0.81 | ALDH1A1 (0.50) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10901615 | 0.71 | TDP1 (0.56) | GAASMN1; SMN2LMNAALDH1A1TDP1 | |
| SCHEMBL9063684 | 0.70 | SIGMAR1 (0.61) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10696254 | 0.70 | SIGMAR1 (0.61) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13675822 | 0.70 | SIGMAR1 (0.61) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10696690 | 0.68 | GAA (0.47) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10767986 | 0.68 | TDP1 (0.48) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14637678 | 0.68 | SIGMAR1 (0.64) | SMN1; SMN2MEN1KMT2ATAAR1 | |
| SCHEMBL12706220 | 0.68 | HPGD (0.64) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |