Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433053 | 1.00 | ACE (0.45) | ACELMNAITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL10771306 | 1.00 | ACE (0.45) | ACELMNAITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL10771310 | 1.00 | ACE (0.45) | ACELMNAITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7433056 | 1.00 | ACE (0.45) | ACELMNAITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7313646 | 0.82 | ITGB3 (0.58) | ACEITGB3ITGA2BPEPD | |
| SCHEMBL7288661 | 0.82 | ITGB3 (0.58) | ACEITGB3ITGA2BPEPD | |
| SCHEMBL8661714 | 0.81 | DPP7 (0.56) | PEPD | |
| SCHEMBL10779423 | 0.81 | ACE (0.43) | ACELMNASMN1; SMN2PEPD | |
| SCHEMBL11050342 | 0.80 | ACE (0.69) | ACELMNASMN1; SMN2 | |
| SCHEMBL683082 | 0.80 | ACE (0.69) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237239-A2 | New compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-09-16 | — | — | EP | disclosed |