Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10767092 | 0.99 | ALDH1A1 (0.43) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL10768874 | 0.79 | MGAM (0.37) | ALDH1A1HCAR3MAPTNPSR1LMNA | |
| SCHEMBL1749879 | 0.76 | NR4A2 (0.59) | RAB9AMAPTNPSR1SMN1; SMN2NR4A2 | |
| SCHEMBL18906070 | 0.76 | MRGPRX4 (0.67) | RAB9AMRGPRX4SMN1; SMN2NR4A2 | |
| SCHEMBL18906044 | 0.75 | TP53 (0.51) | ALDH1A1GAADAORAB9AMAPT | |
| SCHEMBL10515374 | 0.75 | PKM (0.49) | ALDH1A1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL6204996 | 0.74 | NR4A2 (0.65) | ALDH1A1RAB9AMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5176402 | 0.73 | MRGPRX4 (0.53) | ALDH1A1RAB9AMAPTNPSR1MRGPRX4 | |
| SCHEMBL5944017 | 0.71 | NR4A2 (0.63) | MRGPRX4SMN1; SMN2NR4A2MKNK1MKNK2 | |
| SCHEMBL6776797 | 0.71 | CYP4F2 (0.47) | ALDH1A1RAB9AMAPTNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | claimed |