Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515745 | 0.83 | ASPH (0.51) | PLA2G4B | |
| SCHEMBL10515854 | 0.82 | ASPH (0.50) | POLBNPC1RAB9A | |
| SCHEMBL10768870 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HTTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9484774 | 0.74 | RARB (0.41) | ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10767092 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL11328385 | 0.73 | PKM (0.60) | PKMPLA2G4BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9402647 | 0.71 | KMT2A (0.73) | PKMPLA2G4BHTTSMN1; SMN2NR1H4 | |
| SCHEMBL10764581 | 0.71 | HCAR2 (0.41) | ALDH1A1POLBKMT2A | |
| SCHEMBL10722763 | 0.70 | ALDH1A1 (0.49) | PKMPLA2G4BALDH1A1POLBKCNA3 | |
| SCHEMBL312645 | 0.70 | PTPN11 (0.57) | PKMPLA2G4BALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330470-A2 | 1,4-Dihydropyridine derivatives useful against tumour cells | AJINOMOTO CO., INC. (JP) | 1989-08-30 | — | — | EP | claimed |