Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768870 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10767092 | 0.78 | ALDH1A1 (0.43) | MAPTALDH1A1ALOX15NPSR1MEN1 | |
| SCHEMBL10764581 | 0.75 | HCAR2 (0.41) | MGAMKDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL10447248 | 0.74 | MGAM (0.38) | MGAMKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL19857480 | 0.74 | GABRP (0.46) | MGAMKDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL9037560 | 0.74 | HCAR2 (0.40) | MGAMKDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL29819483 | 0.71 | TSHR (0.44) | MGAMKDM4EMAPTALDH1A1TSHR | |
| SCHEMBL10768907 | 0.71 | MGAM (0.38) | MGAMKDM4EPSMD14LMNAKDM4C | |
| SCHEMBL10766358 | 0.70 | HTT (0.53) | MGAMTDP1MAPTALOX15TSHR | |
| SCHEMBL10515374 | 0.69 | PKM (0.49) | ALDH1A1TSHRL3MBTL1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | claimed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | disclosed |