Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.44 |
| ▸ | OXTR | P30559 | 17/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183374 | 0.78 | HCRTR1 (0.45) | HCRTR1HCRTR2OXTRAVPR1AAVPR2 | |
| SCHEMBL6185927 | 0.75 | HPGD (0.43) | — | |
| SCHEMBL1039168 | 0.73 | HCRTR2 (0.72) | HCRTR1HCRTR2OXTRAVPR1AAVPR2 | |
| SCHEMBL1076526 | 0.72 | HPGD (0.39) | — | |
| SCHEMBL6183808 | 0.72 | HCRTR2 (0.42) | HCRTR2 | |
| SCHEMBL6199052 | 0.71 | HIF1A (0.42) | — | |
| SCHEMBL4613644 | 0.71 | HCRTR1 (0.49) | HCRTR1HCRTR2OXTRAVPR1AAVPR2 | |
| SCHEMBL1078296 | 0.70 | PTGER1 (0.44) | — | |
| SCHEMBL4465521 | 0.69 | HCRTR1 (0.55) | HCRTR1HCRTR2OXTRAVPR1AAVPR2 | |
| SCHEMBL6203784 | 0.69 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554239-B1 | SULFONYLAMINO-ACETIC ACID DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-01-26 | — | — | EP | disclosed |