Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074513 | 0.88 | PTGER1 (0.44) | PTGER1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL1078165 | 0.85 | PTGER1 (0.43) | PTGER1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1076164 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6199052 | 0.83 | HIF1A (0.42) | PTGER1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1078008 | 0.81 | KMT2A (0.43) | PTGER1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6203784 | 0.80 | TDP1 (0.39) | PTGER1MEN1KMT2AHPGDLMNA | |
| SCHEMBL1078295 | 0.72 | HCRTR2 (0.56) | PTGER1MEN1KMT2A | |
| SCHEMBL1076948 | 0.70 | HCRTR1 (0.44) | — | |
| SCHEMBL6183374 | 0.67 | HCRTR1 (0.45) | — | |
| SCHEMBL8337800 | 0.67 | PTGER1 (0.62) | PTGER1MEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554239-B1 | SULFONYLAMINO-ACETIC ACID DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-01-26 | — | — | EP | disclosed |