Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107698 | 1.00 | KDM4E (0.52) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrochloric Acid SCHEMBL1574245 | 0.98 | ACE (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrochloric Acid SCHEMBL19332925 | 0.98 | ACE (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1058215 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL25761663 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1058214 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL28854052 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1934656 | 0.80 | TGFBR1 (0.52) | FOLH1SLC7A5NAALAD2TGFBR1ALDH1A1 | |
| SCHEMBL28581576 | 0.80 | TGFBR1 (0.52) | FOLH1SLC7A5NAALAD2TGFBR1ALDH1A1 | |
| SCHEMBL23552453 | 0.80 | KDM4E (0.54) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988008717-A2 | ACTIVE PEPTIDES AGAINST PALUDISM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-11-17 | — | — | WO | claimed |
| US-20240327889-A1 | REGULATION OF CELLS AND ORGANISMS | TETS VICTOR (US) | 2024-10-03 | — | — | US | disclosed |
| CN-113105430-B | Non-natural chiral amino acid compound containing imine sulfone cycloheptyne and salt compound thereof, and preparation method and application thereof | 天津大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-113105430-A | Non-natural chiral amino acid compound containing imine sulfone cycloheptyne and salt compound thereof, and preparation method and application thereof | 天津大学 | 2021-07-13 | — | — | CN | disclosed |
| US-20210121537-A1 | Methods and Compositions for Treating Phenylketonuria | CHILDREN'S NATIONAL MEDICAL CENTER | 2021-04-29 | — | — | US | disclosed |
| US-10792339-B2 | Methods and compositions for treating phenylketonuria | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2020-10-06 | — | — | US | disclosed |
| CN-109310646-A | Delivery-enhancing epinephrine compositions | 阿奎斯蒂弗医疗股份有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109310647-A | Pharmaceutical composition with enhanced penetration | 阿奎斯蒂弗医疗股份有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108513584-A | Ochrobactrum-mediated plant transformation | 先锋国际良种公司 | 2018-09-07 | — | — | CN | disclosed |
| EP-3341483-A1 | OCHROBACTRUM-MEDIATED TRANSFORMATION OF PLANTS | Pioneer Hi-Bred International, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| US-7115735-B2 | Dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20060205045-A1 | Which produces N-alkyl-L-alanine from pyruvic acid and alkylamine or dialkylamine using NADPH and/or NADH as coenzyme; biosynthesis | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-20050124040-A1 | Novel dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-06-09 | — | — | US | disclosed |
| EP-0960944-A1 | Enhanced production of taxol and taxanes by cell cultures of taxus species | PHYTON, INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5367110-A | Chimeric genes comprising dna sequence coding enzymes having kinase and synthase activity; herbicides | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1994-11-22 | — | — | US | disclosed |
| EP-0485970-A2 | Transgenic plants overproducing threonine and lysine | YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) | 1992-05-20 | — | — | EP | disclosed |
| US-5098835-A | Culture of Providencia | TORAY INDUSTRIES, INC. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0292006-B1 | AMINOETHYLCYSTEINE DERIVATIVES | Sanraku Incorporated (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0292006-A1 | Aminoethylcysteine derivatives | Sanraku Incorporated (JP) | 1988-11-23 | — | — | EP | disclosed |
| EP-0271408-A2 | Process for increasing free pool lysine content in maize | SUNGENE TECHNOLOGIES CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205045-A1 | Which produces N-alkyl-L-alanine from pyruvic acid and alkylamine or dialkylamine using NADPH and/or NADH as coenzyme; biosynthesis | ME1, NADK, ME3 | KDM4E 1504/4885MAPT 3690/4885THRB 3336/4885 |
| US-20050124040-A1 | Novel dehydrogenase and a gene encoding the same | ALDH7A1, MDH2, DPYD | KDM4E 1339/4885MAPT 3922/4885THRB 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.