SCHEMBL1077167

SCHEMBL1077167

N#CC1(c2ccc(O)cc2)C2C=CC(C2)C1CC(=O)O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1078394 0.90 KMT2A (0.37) KDM4EKMT2AMEN1ALDH1A1POLB
SCHEMBL4377597 0.88 KDM4E (0.37) KDM4EKMT2AMEN1ALDH1A1POLB
SCHEMBL1739479 0.78 KDM4E (0.36) KDM4EKMT2AMEN1ALDH1A1POLB
SCHEMBL1079211 0.69 HSD11B1 (0.38) KDM4EKMT2AMEN1ALDH1A1POLB
SCHEMBL1078417 0.67 ALDH1A1 (0.44) KDM4EKMT2AMEN1ALDH1A1POLB
SCHEMBL4953534 0.59 HSD11B1 (0.42) KMT2AMEN1
SCHEMBL1078669 0.59 SMN1; SMN2 (0.41) KDM4EKMT2AMEN1ALDH1A1POLB
SCHEMBL6326792 0.58 ITGB3 (0.45) ALDH1A1MIF
SCHEMBL6251346 0.56 MIF (0.35) ALDH1A1MIF
SCHEMBL6317159 0.56 ITGB3 (0.42) KDM4EALDH1A1MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211514-B2 Reverse dispersion retardation film and liquid crystal display device using the same JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-07-03 US disclosed
EP-2390690-A1 INVERSELY DISPERSIVE RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JX Nippon Oil & Energy Corporation (JP) 2011-11-30 EP disclosed
US-7867581-B2 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2011-01-11 US disclosed
US-20090156770-A1 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2009-06-18 US disclosed
EP-2060937-A1 RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME Nippon Oil Corporation (JP) 2009-05-20 EP disclosed