Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483941 | 0.88 | ADRB2 (0.54) | ADRB2SLC6A2SLC6A4ADRB1ADRA1A | |
| Hydrochloric Acid SCHEMBL10769677 | 0.82 | ADRB2 (0.65) | ADRB2SLC6A2SLC6A4ADRB1ADRA1A | |
| SCHEMBL5008661 | 0.78 | ADRB2 (0.52) | ADRB2SLC6A2SLC6A4ADRB1ADRA1A | |
| SCHEMBL10477935 | 0.77 | ADRB2 (0.70) | ADRB2SLC6A2SLC6A4ADRB1ADRA1A | |
| SCHEMBL7381182 | 0.76 | SIGMAR1 (0.57) | ADRB2SLC6A2SLC6A4ADRB1ADRA1A | |
| SCHEMBL10477747 | 0.73 | ADRB2 (0.60) | ADRB2 | |
| SCHEMBL20689716 | 0.72 | CYP2D6 (0.58) | ADRB2SLC6A2SLC6A4ADRB1ADRA1A | |
| SCHEMBL20689721 | 0.72 | CYP2D6 (0.58) | ADRB2SLC6A2SLC6A4ADRB1ADRA1A | |
| SCHEMBL11093917 | 0.71 | SLC2A1 (0.52) | SLC2A1ADRB2SLC6A2SLC6A4ADRB1 | |
| SCHEMBL7317207 | 0.71 | ADRB2 (0.49) | SLC2A1ADRB2SLC6A2SLC6A4ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220878-A2 | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1987-05-06 | — | — | EP | disclosed |