Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cliropamine SCHEMBL2110690 | 0.90 | ADRB2 (0.49) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| Cliropamine SCHEMBL31741642 | 0.89 | SIGMAR1 (0.50) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL7381182 | 0.82 | SIGMAR1 (0.57) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL9483941 | 0.82 | ADRB2 (0.54) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL11807913 | 0.82 | ADRB1 (0.61) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL9973172 | 0.79 | LMNA (0.39) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL10779305 | 0.77 | SIGMAR1 (0.45) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| Hydrochloric Acid SCHEMBL10769677 | 0.75 | ADRB2 (0.65) | ADRB2LMNASLC6A2ADRA1ASLC6A4 | |
| SCHEMBL8974286 | 0.75 | SIGMAR1 (0.45) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL11537605 | 0.75 | ADRB1 (0.47) | ADRB2LMNAHIF1ASLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135905-A2 | 1-(Alkyl-hydroxy-phenyl)-1-hydroxy-2-(alkylamino)-propanes | ASTA Pharma Aktiengesellschaft (DE) | 1985-04-03 | — | — | EP | disclosed |