Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771923 | 0.88 | SLC2A1 (0.48) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL7381182 | 0.87 | SIGMAR1 (0.57) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| Cliropamine SCHEMBL2110690 | 0.82 | ADRB2 (0.49) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL7317207 | 0.82 | ADRB2 (0.49) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| Cliropamine SCHEMBL31741642 | 0.81 | SIGMAR1 (0.50) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL5076478 | 0.77 | LMNA (0.69) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| Hydrochloric Acid SCHEMBL9138402 | 0.76 | LMNA (0.69) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL11807913 | 0.75 | ADRB1 (0.61) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL11918929 | 0.74 | LMNA (0.52) | ADRB2LMNAHIF1ASLC6A2OPRM1 | |
| SCHEMBL11093917 | 0.74 | SLC2A1 (0.52) | ADRB2LMNAHIF1ASLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266589-A | Dihydroxyphenylethanolamine compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-11-30 | — | — | US | disclosed |
| EP-0488435-A1 | Method of increasing the muscle/fat ratio in agricultural domestic animals | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-06-03 | — | — | EP | disclosed |
| EP-0103830-A2 | Phenylethylemine derivatires as growth stimulators | BAYER AG (DE) | 1984-03-28 | — | — | EP | disclosed |