Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322383 | 0.95 | SIGMAR1 (0.37) | SIGMAR1HRH3LSSSLC6A3SLC6A4 | |
| SCHEMBL9321363 | 0.93 | HRH3 (0.42) | HRH3LSSSLC6A4 | |
| SCHEMBL10774584 | 0.93 | HRH3 (0.42) | HRH3LSSSLC6A4 | |
| SCHEMBL10771016 | 0.91 | HRH3 (0.39) | SIGMAR1HRH3LSSSLC6A4 | |
| SCHEMBL10774443 | 0.90 | HRH3 (0.48) | SIGMAR1HRH3LSSSLC6A4 | |
| SCHEMBL9322230 | 0.90 | HRH3 (0.48) | SIGMAR1HRH3LSSSLC6A4 | |
| SCHEMBL9322345 | 0.89 | HRH3 (0.45) | HRH3LSSSLC6A4 | |
| SCHEMBL9322241 | 0.88 | HRH3 (0.45) | SIGMAR1HRH3LSSSLC6A4 | |
| SCHEMBL9322161 | 0.88 | HRH3 (0.41) | HRH3LSSSLC6A4 | |
| SCHEMBL9322145 | 0.88 | HRH3 (0.41) | HRH3LSSSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235942-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |