Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | HTR1D | P28221 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.61 |
| ▸ | HTR3B | O95264 | 2/20 | 0.61 |
| ▸ | HTR1B | P28222 | 2/20 | 0.61 |
| ▸ | HTR1E | P28566 | 2/20 | 0.61 |
| ▸ | HTR1F | P30939 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | HTR3A | P46098 | 2/20 | 0.61 |
| ▸ | HTR5A | P47898 | 2/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973250 | 0.89 | HTR2A (0.66) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL31079780 | 0.89 | HTR2A (0.66) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL10770864 | 0.85 | HTR1A (0.61) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL10772090 | 0.85 | HTR1A (0.61) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL32669398 | 0.80 | HTR1A (0.66) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL30249043 | 0.76 | HTR1D (1.00) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL20970981 | 0.76 | HTR1D (1.00) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL27077936 | 0.76 | HTR2A (0.65) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL32669266 | 0.74 | MPO (0.59) | HTR2AHTR1AHTR1DHTR2CHTR3E | |
| SCHEMBL27078020 | 0.74 | HTR2A (0.62) | HTR2AHTR1AHTR1DHTR2CHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248187-A2 | Indole derivative | MERCK PATENT GmbH (DE) | 1987-12-09 | — | — | EP | disclosed |